Campaign Low-HP Shield Team: Ether · Liter · Modernia · Drake · 1 flex Attacker. Burst "Colossal Single Cell" shields the 3 lowest-HP allies for 96% Max HP, saving the squad on heavy stages before full gear; Skill 2 lowers enemy DEF during Full Burst, boosting Modernia/Drake's damage. Arena/PvP AoE-Proof Team: Ether · Quency · 1 flex Supporter · Drake · Power. Shielding the 3 lowest-HP allies for 96% Max HP nearly nullifies one opening AoE burst, buying carries time to counter. Raid & Interception Sustained Damage Reduction Team: Rei · Ether · Biscuit · Guilty · 1 flex Attacker. Skill 1 cuts sustained damage on the lowest-HP ally by 52.5%, extremely useful against boss poison/drain effects; Rei/Biscuit healing sustains the rest.

Ether — Stats, Skills, Best Teams

Q: Should you pull?

Should you pull?CONSIDER IT — as an SR she does not demand heavy gem investment the way limited SSR banners do; worth keeping as a stopgap Defender for newer players or anyone lacking a shield/sustained-damage-reduction unit, but not worth chasing specifically since SR units are also obtainable through normal sources (standard recruit, events).

Q: Skill Investment Priority

Skill investment roadmap (Skill 1/Skill 2/Burst): 4/4/4 → 7/4/7 → 10/4/10. Why: Skill 1 (sustained damage reduction) and Burst (AoE shield) are her two main survival tools and should come first; Skill 2 is only a secondary DEF-shred effect, so it can wait.

30-second summary of Ether

Ether is a Electric Nikke in the Defender class, manufactured by Missilis. Stats and skill text below come straight from the game's data.

“A classic couch potato. She perks up, however, whenever performing experiments or engaging in battle.”

Updated: 2026-08-02

Should you pull?

CONSIDER IT — as an SR she does not demand heavy gem investment the way limited SSR banners do; worth keeping as a stopgap Defender for newer players or anyone lacking a shield/sustained-damage-reduction unit, but not worth chasing specifically since SR units are also obtainable through normal sources (standard recruit, events).

Review & Analysis

Ether is an Electric Defender (SR) built to protect the squad's weakest link. Her Burst, Colossal Single Cell, shields the 3 lowest-HP allies for 96% of her own max HP for 5 seconds. Prognostic Response Experiment hits the 3 highest-DEF enemies for 56.32% of ATK, and during Full Burst also shreds those targets' DEF by 9.38% for 6 seconds. Corrosive Bullets cuts Sustained Damage on the lowest-HP ally by 52.5% for 5 seconds. As an SR unit, she sits at tier E.

Base Stats

HP307,885

ATK8,666

DEF2,459

Max Ammo9

Reload Time2s

Skills

Normal Attack

■ Affects target(s).
Deals 214.3% of ATK as damage.

Corrosive BulletsSkill 1

■ Affects 1 allies with the lowest HP.
Sustained Damage ▼ 52.5% for 5 sec.

Prognostic Response ExperimentSkill 2

■ Affects 3 enemy unit(s) with the highest DEF.
Deals 56.32% of ATK as damage.
■ Affects the same enemy unit(s) Activates during Full Burst.
DEF ▼ 9.38% for 6 sec.

Colossal Single CellBurst Skill

■ Affects 3 ally unit(s) with the lowest HP.
Creates a Shield equal to 96% of the caster's Max HP for 5 sec.

Skill Investment Priority

Burst first — her main shield, the core of her protective value. Skill 2 next for the DEF-shred plus its own damage. Skill 1 last, since it only helps one lowest-HP ally at a time.

Skill investment roadmap (Skill 1/Skill 2/Burst): 4/4/4 → 7/4/7 → 10/4/10. Why: Skill 1 (sustained damage reduction) and Burst (AoE shield) are her two main survival tools and should come first; Skill 2 is only a secondary DEF-shred effect, so it can wait.

Strengths & Weaknesses

Strengths

Her Burst grants a shield worth 96% Max HP to the 3 lowest-HP allies — a sizable AoE shield for an SR-tier unit.
Skill 1 cuts sustained damage taken by low-HP allies by 52.5%, a solid survival tool for teams lacking a healer.
Skill 2 both deals damage and lowers DEF on the highest-DEF target during Full Burst, giving her some anti-tank utility.

Weaknesses

As an SR, her base stats and power ceiling sit below dedicated SSR Defenders.
Her shield/damage-reduction only targets the lowest-HP ally, not the whole squad evenly.
No active taunt/aggro mechanic, so her tanking effectiveness trails a dedicated taunt Defender.

Overload Priority

Overload priority by weapon type — applies to every Nikke using this weapon.

Sub-stat	Priority	Rolls
ATK		4x
Max Ammo		2-4x
Hit Rate		1-4x
Elemental DMG		2x

Gear →

General Info

Meta Tier

D

Class

Defender

Element

Electric

Weapon Type

SG

Manufacturer

Missilis

Squad

M.M.R.

Voice Actors

Bang Siu · Lisa Ortiz · Sayaka Senbongi

Release date

4 nov 2022

Recommended Build

Cubes

Vigor Cube / Resilience Cube

Overload (OL) Priority

Increase ATK › Increase Hit Rate › Increase Element Damage Dealt

Suggested by role & weapon. See: Gear · Cubes

Recommended Teams

Campaign

Low-HP Shield Team: Ether · Liter · Modernia · Drake · 1 flex Attacker. Burst "Colossal Single Cell" shields the 3 lowest-HP allies for 96% Max HP, saving the squad on heavy stages before full gear; Skill 2 lowers enemy DEF during Full Burst, boosting Modernia/Drake's damage.

Arena/PvP

AoE-Proof Team: Ether · Quency · 1 flex Supporter · Drake · Power. Shielding the 3 lowest-HP allies for 96% Max HP nearly nullifies one opening AoE burst, buying carries time to counter.

Raid & Interception

Sustained Damage Reduction Team: Rei · Ether · Biscuit · Guilty · 1 flex Attacker. Skill 1 cuts sustained damage on the lowest-HP ally by 52.5%, extremely useful against boss poison/drain effects; Rei/Biscuit healing sustains the rest.