Semmelweis
Semmelweis is a 6★ Mineral Arcanist in Reverse: 1999. Below are the exact Insight materials needed to ascend them, plus other Mineral Arcanists to build alongside.
Data updated: 2026-07-11
Semmelweis — Review & Analysis
Semmelweis is a hybrid support-DPS built entirely around an HP-sacrifice team. Her Ultimate lays down the [Bloodred Domain] formation that cuts 20% incoming DMG and stacks a DMG bonus each time an ally loses HP, while [Fine Trick] grants up to +30% team-wide DMG plus a Crit Rate buff through [New Blood]. Her standout is the AoE [Truth Revealed], whose Reality DMG scales with how many times the whole team loses HP (up to 20 stacks of +30%), turning a self-harm comp into a fast wave-clearer.
- Many roles in one: team-wide DMG buff (up to +30%), Crit Rate via [New Blood], and a flat 20% DMG reduction — offense and defense together.
- The AoE [Truth Revealed] multiplies its Reality DMG per team-wide HP loss (up to 20 stacks of +30%), so the more HP-sacrifice your team runs, the harder it hits.
- Mineral Afflatus counters Beast (+30% DMG in that matchup), and her Insight self-generates Passion (+3 on entry, +1 after Ultimate) for smoother rotations.
- Locked into an HP-sacrifice structure: outside a self-harm comp with sustain, her payoff drops sharply.
- Constant team-wide HP drain is risky against burst enemies, and she's countered by the Intellect Afflatus (takes +30% DMG).
Level the Ultimate first — [Bloodred Domain] plus [Truth Revealed] is her identity and main damage engine — then [Fine Trick] to max the team DMG and Crit buffs, leaving [Iron Nameplate] for last. For Psychubes, lean toward ATK/Crit options to amplify [Truth Revealed]'s Reality DMG, or a healing/HP-management one to keep the HP-loss loop stable.
Overview
Base Stats (max level)
| Base Stats (max level) | Lv.1 | Lv.30 | Insight 1 · Lv.40 | Insight 2 · Lv.50 | Insight 3 · Lv.60 |
|---|---|---|---|---|---|
| HP | 1,360 | 2,064 | 3,461 | 5,161 | 6,072 |
| ATK | 254 | 385 | 646 | 963 | 1,133 |
| Reality DEF | 128 | 194 | 326 | 486 | 572 |
| Mental DEF | 128 | 194 | 326 | 486 | 572 |
| Crit Rate | 9.1% | 9.1% | 10.3% | 11.5% | 12.7% |
| Crit DMG | 143.7% | 143.7% | 145.4% | 147.3% | 149.1% |
Semmelweis — Skills & Incantations
Rise Thus, Rise
Ultimate “Insight II: Mass buff. All allies lose (Current HP x20%) HP. Creates a special array 【Blood Domain】 for 3 rounds. Enters the 【Feral Instinct】 status for 3 rounds.”
Iron Nameplate
Incantation “Insight II: 1-target attack. Loses (Current HP x10%) HP and deals 550% Reality DMG.”
Fine Trick
Incantation “Insight II: 1-target buff. Grants the 【Fresh Blood】 status to an ally for 2 rounds, then grants DMG Dealt +30% to all allies and an additional DMG Dealt +10% to the ally in the 【Fresh Blood】 status for 2 rounds.”
Insight Legacy
Incantation “Insight I: When entering battle, lose own (Current HP x20%) HP and grant Moxie +3 to self.”
Skill Quotes
“It watches her six.”
“It watches her six, though not the most reliable ally.”
“It watches her six. Not the most reliable ally, but better than having nothing at all.”
“Let the moon witness her transformation.”
“Let the moon witness her transformation and hypocrisy.”
“Let the moon witness her transformation, her hypocrisy, and the only hope that lies behind her madness.”
“It was on this night that she turned. Tomorrow, and for the rest of her life, she will remain what she has become.”
Insight Materials
Insight 1
Insight 2
Insight 3
Resonance Materials
All 14 Resonance levels
Euphoria
Branch 1
Whenever an ally loses HP, accumulates points of [Bloodtithe]. When entering battle, gain Max HP +50% and grant (Semmelweis's Max HP x10%) Max HP to other allies.
For every 8 [Bloodtithe] points gained by the team, gain Moxie +1 for self. [Truth Revealed] deals (30% of own Max HP instead of ATK) Reality DMG plus 100% Reality DMG and grants [Bloodtithe] points +2.
[Blood Domain] Additional Effects: All allies' Healing Taken +10%. For every 10% missing Max HP on allies, they gain an additional Healing Taken +4% (up to 32%). When under [Blood Domain], if max [Bloodtithe] reaches 50/70, after an ally takes an action, they lose 5% of current HP and gain Extra Action DMG Dealt +15%/30%. If the ally has [Fresh Blood], they gain an additional Extra Action DMG Dealt +10%/20%.
Recommended Psychubes
Where to Get
Teams with Semmelweis
Semmelweis and Getian both drop an Array and tag Moxie — placing them together means their Array effects and Moxie generation overlap on the field instead of competing for the same square. Sentinel and Rubuska both carry Bloodtithe, converting the extra Crit/Heal actions the Array encourages into a shared resource pool.
Teams →
Tuesday, Semmelweis and Getian all tap into Array together with Poison — combining it across three kits at once outperforms any single carry doing it alone. Kiperina keeps the line-up alive with Shield so that payoff has time to land.
Teams →Sentinel, Rubuska and Moldir all tap into Bloodtithe together with Crit — combining it across three kits at once outperforms any single carry doing it alone. Kiperina keeps the line-up alive with Shield so that payoff has time to land.
Teams →
Nautika and Semmelweis both spend HP as a resource instead of hoarding it — Nautika's Incantations trade her own Current HP for extra Reality DMG, and Semmelweis's Ultimate costs every ally 20% Current HP to drop the 【Blood Domain】 Array. Sentinel and Rubuska both carry the same passive that turns any ally's HP loss into shared 【Bloodtithe】, so every point the front two spend feeds the Bloodtithe that Sentinel cashes in on 【Dread Bullet】 bursts and Rubuska turns back into team healing.
Teams →
